Medical Marijuana and ALS

Medical Marijuana offers relief from neurological symptoms, including muscle spasms, seizures, and involuntary movements. ALS patients report easier breathing, reduced salivation, and less pain, along with improvement in mood and more regular sleep patterns.


Growing evidence suggests Marijuana-based therapies (Cannabinoids) may work better than current FDA-approved medication in treating ALS; research suggests Marijuana’s antioxidative, anti-inflammatory, and neuroprotective properties could slow disease progression.

Cannabis has also demonstrated efficacy in treating the following ALS symptoms:

  • Sleep
  • Fatigue
  • Memory
  • Appetite
  • Mood
  • Reaction Time
  • Paranoia

According to a 2010 study published by Rehabilitation Medicine and Palliative Care:

“Ideally, a multi-drug regimen, including glutamate antagonists, antioxidants, a centrally acting anti-inflammatory agent, microglial cell modulators (including tumor necrosis factor alpha [TNF-a] inhibitors), an antiapoptotic agent, one or more neurotrophic growth factors, and a mitochondrial function-enhancing agent would be required to comprehensively address the known pathophysiology of ALS.

Remarkably, Marijuana appears to have activity in all of those areas. Preclinical data indicate that Marijuana has powerful antioxidative, anti-inflammatory, and neuroprotective effects.”